The calamity continues with the latest Cartoon Network Crossover Crisis game! Animation Annihilation is a standalone game and 100% compatible with 2016's Cartoon Network Crossover Crisis Deck-Building Game. New to the party are heroes and rivals from Cartoon Network's past and present hit shows like Powerpuff Girls, Adventure Time, Uncle Grandpa, Cow and Chicken, The Grim Adventures of Billy & Mandy, and Ed, Edd n Eddy.