Villainy: The Supervillainous Card Game (2005)

An expandable (non-collectible) card game, Villainy - The Supervillainous Card Game pits players against each other in a bid for world domination. The first set, titled Evil Masterminds, lets players choose one of three villains to play: Mugga Mugga, Dr. Oblongata, or Mallory Maleficarum. Future sets will be based around Dregs of Society and Scum of the Earth.

From the publisher:

Villainy - The Supervillainous Card Game pits cartoon evildoers against each other in a bid for world domination...or at least bragging rights at the next bad guy potluck.

Each 60-card deck is packed with weapons, minions, monsters, and special action, segue, and set-up cards that really shake things up! In their bid for control of the planet, the super villains must employ everything at their disposal, and in the end ONLY ONE CAN WIN!

Each deck in the set is sold separately. Choose your favorite bad guy or collect them all!