Mise: Kolonizace is a quick and simple tile-laying game with a slight Carcassonne feel and the theme of colonizing Mars. Each player starts the game with the same drawing deck of tiles (with the only difference being the color of the astronauts on the tiles) of which they draw one, then play one until everyone has only two tiles left.
When you place a tile, you may connect same-colored areas freely — there are three tile colors — but different-colored areas must be separated by laser "walls", some of which have green "doors" on them. When such a same-colored area is completely enclosed by laser walls, it is evaluated. The player with the most astronauts in the area gets the points; in case of a tie, the points are divided between the players. An area is worth 1 point for each tile and 3 points for each alien there, but what makes the game tricky is that you get these points also for those neighboring areas (not only the closed ones) that are connected by doors to the evaluated area.
At game end, score 2 points for each astronaut and alien on the tiles you have left. Whoever has the most points wins.