M.U.L.E. The Board Game from designer Heikki Harju debuts at Spiel 2015 in October and is scheduled for a worldwide launch in November 2015. Here's a summary of the setting and gameplay from the publisher:
In M.U.L.E. The Board Game, you are one of the pioneering and industrious species of a Galactic Federation. Together with your fellow colonists, you attempt to settle the distant Planet Irata with the so-called help of a mule-like machine you all learn to hate. But for now, he's all you've got. Well, him and your fellow colonists. I wouldn't count on their help, though — not unless there's profit. Good luck. You'll need it.
In more detail, on Irata you claim plots of land, fit M.U.L.E.s (Multiple Use Labor Elements) for harvesting of food, energy, and smith ore as well as the exclusive and elusive crystite. The most cunning settler and trader receives fame, fortune, and the honorary title of first colonist!