Each round in The Towers of Arkhanos, you draft a die — or two dice in a two-player game — then place it one of the four towers. Each of the three exterior towers has building restrictions on the numbers and colors of dice that can be placed there, while the central tower can take any die. When you place a die in the exterior tower, you score points, gain the ability to place one of your figures in another tower (giving you influence there), or claim a spell ability for use later.
When a tower level is filled with three dice or figures, players score points based on their influence on that level, then you add a new level tile on top of the dice and figures to continue building. After eight or nine round based on the number of players, you see who's piled up the most influence and wins.
I've played The Towers of Arkhanos five times on a review copy with two and three players, and while the game works, we continually ran into situations in which you had no choice but to place a die in the central tower, despite us often having die-manipulation spell powers that should let us have more choices for where to play. I go into this situation in more detail in this video: