Zagami (2002)

Zagami is a game of Martian microbial life for four players. It requires a standard chessboard and a set of Icehouse Pieces.

Each player controls a single-colored colony of microbes, which moves and expands across the small meteorite in search of food. Multicolored stacks begin to form - microbes eating microbes eating microbes. As the game progresses, each colony evolves "enzymes" which allow it to metabolize other microbes into energy to be used for growing, sporing, attacking, and escaping. Only one colony will survive the long journey from Mars to Earth. Will it be yours?